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Arlen Animal Shelter is an animal shelter located in Arlen.

In To Kill a Ladybird, Hank goes to the animal shelter to post a missing dog sign on a bulletin board after Lady Bird runs off, chasing Bandit.

In Hillennium, during the Y2K hysteria, Hank gives Dale and Chappy the task of gathering food, while Hank focuses on supplies. Dale and Chappy go to the animal shelter with the intent of adopting a dog for food.

In Dances With Dogs, Bill, eager to enter a dog-dancing competition, goes to the animal shelter and adopts an aggressive Rottweiler named Rex, which viciously attacks Bill, causing him to be in constant fear.